منابع مشابه
PARP1 – Another factor of stemness?
Received: July 25, 2016; Accepted: August 08, 2016; Published: August 08, 2016 The pluripotency of embryonic stem cells, which are capable of unlimited self-renewal and differentiation into every type of cell in the body, is provided by the extensive expression of genes encoding stemness factors, among which the transcription factors such as Sox2, Pou5f1, Nanog are most frequently enumerated [1...
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Erik von Elm PLoS Medicine now encourages translations in languages other than English; this decision can only be welcomed. German-speaking readers are pleased by the novelty of a PLoS title written in their language. The Editorial starts with the fi rst line of the well-known German poem “Lorelei” by Heinrich Heine (1797–1856) [1]. This year commemorates the 150th anniversary of his death. Ori...
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Poly (ADP-ribose) polymerase 1 (PARP1), the best-studied isoform of the nuclear enzyme PARP family, plays a pivotal role in cellular biological processes, such as DNA repair, gene transcription, and so on. PARP1 has been found to be overexpressed in various carcinomas. These all indicate the clinical potential of PARP1 as a therapeutic target of human malignancies. Additionally, multiple precli...
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ژورنال
عنوان ژورنال: Molecular Biophysics and Biochemistry
سال: 2016
ISSN: 2398-970X
DOI: 10.15761/mbb.1000101